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Add-Ons

Add-ons enable additional capabilities in ElemBio Cloud and AVITI OS. The Add-Ons page displays the add-ons for your organization. The View History button displays add-on history for the organization.

To enable or renew an add-on, contact Element Technical Support or a sales representative.

Add-On Features​

The Add-Ons page displays cards for each add-on for your organization. The cards display the following information:

  • Add-on name and description
  • Instrument availability
  • Icons for impacted products, such as the AVITI System or ElemBio Cloud
  • An expiration date or No Expiry badge
  • A subscription term or Lifetime badge
Note:

When an add-on expires, the card displays a red badge with the date of expiration for the next 30 days. After 30 days, the card disappears, and a record of the add-on only appears in the add-on history.

ElemBio Catalyst​

ElemBio Catalyst is a subscription-based native data storage and analysis add-on within ElemBio Cloud. For more information, see ElemBio Catalyst.

Individually Addressable Lanes​

The Individually Addressable Lanes add-on enables loading two library pools, one in each lane of a flow cell. The second library is loaded into the AUX well of the sequencing cartridge. Enabling individually addressable lanes enacts the following run planning changes:

  • When you add a planned run and choose a compatible sequencing kit, the option to select a number of library pools becomes available.
  • Planned runs that use individually addressable lanes become unavailable on instruments without the add-on. For more information on planned run compatibility, see the compatibility table for run planning.

Kit Compatibility for Individually Addressable Lanes​

The Individually Addressable Lanes add-on is only compatible with sequencing kits that meet the following requirements:

  • Cloudbreak or Cloudbreak Freestyle chemistry
  • 2 x 75 and 2 x 150 size
  • A high-, medium-, or low-output designation.
Caution:

The Individually Addressable Lanes add-on is not compatible with any 2 x 300 size sequencing kits or Cloudbreak UltraQ sequencing kits. The cartridges in these kits reserve the AUX well for other reagents and cannot accommodate a second library.

Advanced Run Settings​

The Advanced Run Settings add-on allows experienced users to modify primary analysis and recipe configurations for runs. The add-on includes various features, which Element can enable or disable. Cloudbreak UltraQ is not compatible with these features.

Enabling the Advanced Run Settings add-on enacts the following run planning changes:

  • When you add a planned run and choose a compatible sequencing kit, ElemBio Cloud enables the options to select available settings for the feature.
  • Planned runs that use a feature become unavailable on instruments without the specific feature enabled. For more information, see the compatibility table for planned runs.

Polony Density​

The Polony Density feature relaxes certain quality filters to increase the total number of polonies in a run. The setting has two options, with Standard as the default option. The High Density option increases the read output. This feature is also known as Expert Mode HD.

Filter Mask​

The Filter Mask feature modifies the cycles used for filtering, which is advantageous for certain applications. Applying the feature causes run output data and on-instrument run metrics to account for the filter mask.

Custom Recipes​

The Custom Recipe feature tailors a run execution in consultation with Element by enabling a custom recipe. A recipe governs the stages of a sequencing run, so custom recipes can impact specifications and significantly increase run times.

The setting for the feature provides two options for using custom recipes with a run:

  • Preloaded recipe: Select a recipe already loaded onto AVITI Systems, such as short insert and long insert custom recipes. Before using a preloaded recipe, contact Element Technical Support to ensure run compatibility.
    • Short Insert Recipe: If you are using Cloudbreak Freestyle chemistry and libraries with ≤ 100 bp DNA inserts, such as miRNA libraries, use the short insert recipe. The recipe is only compatible with 2 x 75 and 2 x 150 sequencing kits.
    • Long Insert Recipe: If you are using Cloudbreak or Cloudbreak Freestyle chemistry and libraries with > 1000 bp DNA inserts, use the long insert recipe. The recipe is only applicable for 2 x 75 and 2 x 150 sequencing kits, as 2 x 300 sequencing kits already account for long insert conditions.
  • Uploaded recipe: Element creates and prepares an encrypted, custom recipe package as a .rec file, which you can then upload to use with your run. To obtain a custom recipe to upload, contact Element Technical Support.

High Output Kits​

The High Output Kits add-on enables sequencing with high-output kits. Planned runs that use high-output kits become unavailable on instruments without the add-on.

Download an Add-On Key for Offline Instruments​

Add-ons sync automatically with online instruments. For offline instruments, you must download a product key from the Add-Ons page to complete installation. The key remains valid for 7 days after the download and applies to all add-ons available for your organization at the time of download.

The following steps prepare the key for installation:

  1. Connect a USB drive to a USB port on your computer.
  2. On the Add-Ons page, select Download Add-On Key.
  3. Move the downloaded instrument-add-ons.tar.gz file to the root folder of the USB drive.
  4. Complete installation as instructed in the Element AVITI System User Guide (MA-00008).
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